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Shumpei Yokota Selected Research

Juvenile Arthritis (Juvenile Idiopathic Arthritis)

3/2021Safety and effectiveness of adalimumab in Japanese patients with juvenile idiopathic arthritis: Results from a real-world postmarketing study.
1/2021Efficacy and safety of canakinumab in systemic juvenile idiopathic arthritis: 48-week results from an open-label phase III study in Japanese patients.
4/2019Intravenous abatacept in Japanese patients with polyarticular-course juvenile idiopathic arthritis: results from a phase III open-label study.
1/2018Safety and effectiveness of etanercept for treatment of juvenile idiopathic arthritis: Results from a postmarketing surveillance.
1/2017PADI4 and the HLA-DRB1 shared epitope in juvenile idiopathic arthritis.
1/2016Tocilizumab in systemic juvenile idiopathic arthritis in a real-world clinical setting: results from 1 year of postmarketing surveillance follow-up of 417 patients in Japan.
4/2015Macrophage Activation Syndrome in Patients with Systemic Juvenile Idiopathic Arthritis under Treatment with Tocilizumab.
1/2015Pathogenesis of systemic inflammatory diseases in childhood: "Lessons from clinical trials of anti-cytokine monoclonal antibodies for Kawasaki disease, systemic onset juvenile idiopathic arthritis, and cryopyrin-associated periodic fever syndrome".
7/2014Effect of tocilizumab on growth impairment in systemic juvenile idiopathic arthritis with long-term corticosteroid therapy.
6/2014Discrepancy between clinical and radiological responses to tocilizumab treatment in patients with systemic-onset juvenile idiopathic arthritis.
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Shumpei Yokota Research Topics

Disease

42Juvenile Arthritis (Juvenile Idiopathic Arthritis)
03/2021 - 09/2003
12Mucocutaneous Lymph Node Syndrome (Kawasaki Disease)
01/2017 - 01/2004
11Infections
02/2021 - 12/2002
10Inflammation (Inflammations)
02/2021 - 12/2002
10Fever (Fevers)
01/2015 - 09/2003
8Rheumatic Diseases (Rheumatism)
05/2016 - 04/2002
8Systemic Lupus Erythematosus (Libman-Sacks Disease)
03/2015 - 04/2002
8Disease Progression
12/2013 - 09/2003
7Arthritis (Polyarthritis)
01/2018 - 09/2003
7Macrophage Activation Syndrome
04/2015 - 09/2003
7Leukemia
01/2014 - 10/2003
6Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2013 - 10/2003
5Cryopyrin-Associated Periodic Syndromes
11/2017 - 01/2012
4Cytokine Release Syndrome
02/2021 - 11/2003
4Takayasu Arteritis (Arteritis, Takayasu's)
01/2020 - 01/2010
4Rheumatoid Arthritis
01/2017 - 04/2002
4Dermatomyositis (Dermatopolymyositis)
12/2015 - 12/2002
4Chorioamnionitis
10/2014 - 07/2003
4Neoplasms (Cancer)
01/2014 - 06/2004
3Tuberculosis (Tuberculoses)
05/2016 - 12/2005
3Lupus Nephritis
03/2015 - 04/2002
3Asthma (Bronchial Asthma)
12/2012 - 04/2007
3Human Influenza (Influenza)
11/2012 - 04/2007
3Proteinuria
08/2010 - 04/2007
3Lung Diseases (Lung Disease)
04/2010 - 07/2003
3Abdominal Pain (Pain, Abdominal)
01/2010 - 06/2006
3Hypersensitivity (Allergy)
04/2007 - 09/2004
2Communicable Diseases (Infectious Diseases)
02/2021 - 01/2012
2Polyarteritis Nodosa (Periarteritis Nodosa)
07/2018 - 10/2008
2Melanoma (Melanoma, Malignant)
12/2015 - 05/2015
2Muscular Diseases (Myopathy)
05/2014 - 11/2012
2Pain (Aches)
08/2013 - 01/2013
2Drug-Related Side Effects and Adverse Reactions
05/2013 - 12/2005
2Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome)
02/2013 - 02/2008
2Body Weight (Weight, Body)
11/2012 - 01/2005
2Muscle Weakness
11/2012 - 12/2002
2Congenital Heart Defects (Congenital Heart Defect)
01/2012 - 06/2010
2Anemia
09/2010 - 10/2008
2Calcinosis
02/2010 - 06/2003
2Neuroblastoma
07/2008 - 01/2008
2Graft vs Host Disease (Graft-Versus-Host Disease)
02/2008 - 07/2006
2Lymphoma (Lymphomas)
10/2007 - 10/2003

Drug/Important Bio-Agent (IBA)

24tocilizumab (atlizumab)FDA Link
01/2020 - 03/2005
12SteroidsIBA
01/2020 - 09/2003
9CytokinesIBA
02/2021 - 01/2004
9Adrenal Cortex Hormones (Corticosteroids)IBA
01/2016 - 09/2003
9Interleukin-6 (Interleukin 6)IBA
01/2014 - 09/2003
8Monoclonal AntibodiesIBA
01/2015 - 12/2008
8Pharmaceutical PreparationsIBA
12/2013 - 04/2002
7C-Reactive ProteinIBA
04/2019 - 03/2007
7Cyclosporine (Ciclosporin)FDA LinkGeneric
08/2014 - 07/2006
7Prednisolone (Predate)FDA LinkGeneric
12/2013 - 04/2002
6canakinumabFDA Link
01/2021 - 01/2012
6Biological ProductsIBA
07/2018 - 07/2007
6Intravenous Immunoglobulins (IVIG)FDA Link
04/2015 - 02/2007
6MethylprednisoloneFDA LinkGeneric
05/2014 - 10/2005
6Cyclophosphamide (Cytoxan)FDA LinkGeneric
05/2014 - 12/2002
6Methotrexate (Mexate)FDA LinkGeneric
01/2014 - 01/2005
5Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2020 - 09/2003
5Immunosuppressive Agents (Immunosuppressants)IBA
07/2018 - 10/2003
5Etanercept (Enbrel)FDA Link
01/2018 - 01/2005
5Biomarkers (Surrogate Marker)IBA
01/2017 - 01/2005
5AntibodiesIBA
05/2015 - 06/2006
5Infliximab (Remicade)FDA Link
01/2015 - 12/2008
4Adalimumab (Humira)FDA Link
03/2021 - 08/2012
4mizoribineIBA
02/2009 - 04/2002
4gamma-Globulins (gamma-Globulin)IBA
02/2007 - 01/2004
3fibrin fragment D (D-dimer)IBA
04/2015 - 10/2008
3Mycophenolic Acid (Cellcept)FDA LinkGeneric
03/2015 - 02/2008
3EnzymesIBA
08/2013 - 12/2002
3Indicators and Reagents (Reagents)IBA
08/2012 - 01/2005
3Immunoglobulins (Immunoglobulin)IBA
02/2012 - 05/2004
3Prostaglandins EIBA
01/2012 - 11/2006
3Alanine Transaminase (SGPT)IBA
02/2011 - 03/2006
3DNA (Deoxyribonucleic Acid)IBA
08/2010 - 05/2004
3anti-dsDNA autoantibodyIBA
08/2010 - 06/2008
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2010 - 12/2008
3Glutathione (Reduced Glutathione)IBA
07/2008 - 10/2003
2Oligonucleotide ProbesIBA
01/2017 - 03/2011
2HLA-DRB1 Chains (HLA DRB1)IBA
01/2017 - 09/2004
2InterferonsIBA
05/2016 - 10/2008
2Proteins (Proteins, Gene)FDA Link
10/2014 - 06/2006
2Signal Recognition ParticleIBA
05/2014 - 11/2012
2InterleukinsIBA
05/2013 - 08/2009
2Fructose-Bisphosphate Aldolase (Aldolase)IBA
01/2013 - 12/2002
2Influenza Vaccines (Influenza Vaccine)FDA Link
11/2012 - 04/2007
2Hyaluronic Acid (Hyaluronan)IBA
01/2012 - 09/2007
2Antirheumatic Agents (DMARD)IBA
12/2011 - 04/2010
2Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
04/2009 - 11/2004
2Interferon-gamma (Interferon, gamma)IBA
02/2009 - 12/2005
2beta 2-Microglobulin (beta 2 Microglobulin)IBA
10/2008 - 07/2003
2Reactive Oxygen Species (Oxygen Radicals)IBA
07/2008 - 10/2003

Therapy/Procedure

34Therapeutics
05/2016 - 04/2002
8Plasma Exchange
05/2014 - 01/2004
5Drug Therapy (Chemotherapy)
10/2011 - 06/2004
3Hematopoietic Stem Cell Transplantation
01/2018 - 01/2008
2Aftercare (After-Treatment)
07/2013 - 09/2004
2Transplantation
03/2008 - 02/2008
2Stem Cell Transplantation
01/2008 - 07/2006
2Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
01/2008 - 07/2006